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991.
胡萝卜籽挥发油的抗生育作用 总被引:3,自引:0,他引:3
胡萝卜籽挥发油对小鼠有抗着床,抗早、中和晚期妊娠作用。对大鼠也有抗着床作用。挥发油中的萜类碳氢化合物部位,对小鼠皮下注射抗早期妊娠的ED_(50)为2.9ml/kg,甲地孕酮和hCG能明显逆转其作用;对假孕小鼠蜕膜瘤有抑制作用,此作用不能被甲地孕酮拮抗,皮下注射于早孕大鼠24、48小时后血浆孕酮浓度明显下降。以上提示其抗早孕作用机制可能与抑制孕酮合成和蜕膜反应有关。此外,挥发油碳氢部分无雌激素和抗雌激素活性,低浓度时对早孕大鼠离体子宫的收缩活动没有影响,高浓度则表现抑制作用。 相似文献
992.
993.
本文报道10例主动脉性咽下困难。病因为高血压和/或主动脉硬化。X线特征为:①下段食管不完全梗阻;②梗阻端正位呈两种不同形态:一为梳齿状;一为偏心性狭窄。左、右前斜位均为尖端指向前的偏心性狭窄;③受压移位食管左前斜位呈正“C”字形,右前斜位是反“C”字形,“C”字内有降主动脉断面致密影;④移位食管内之粘膜扭曲交叉。 相似文献
994.
British Medical Association. Working Party on the Involvement of Doctors in Torture 《Lancet》1986,1(8481):628-629
In 1984 the Council of the British Medical Association set up a working party, chaired by J.P. Quillam, to investigate claims that doctors in some countries were cooperating with the use of torture as a routine instrument of repression. The conclusions and recommendations of the working party's recently published report are reproduced here, along with a list of the members of the working party. Among the report's conclusions [which are reproduced also in the British Medical Journal 1986 Mar 15; 292(6522): 781-782] are that doctors have a responsibility to support any practitioner who refuses to keep silent about abuses of human rights, to check for signs of physical abuse of prisoners, and to publicize any violations of the Declaration of Tokyo. Physicians are also encouraged to offer their services to organizations such as the Medical Foundation for the Care of Victims of Torture. 相似文献
995.
Dr. Gennaro D'amico MD Alberto Morabito MS Luigi Pagliaro MD Ettore Marubini MD The Liver Study Group of “V. Cervello” Hospital 《Digestive diseases and sciences》1986,31(5):468-475
Six-year survival of cirrhosis was assessed in a series of 1155 consecutive patients (751 men, 404 women). Among the men, 33% were alcoholics and 18% were HBsAg positive; corresponding figures for the women were 15% and 6%, respectively. Features of decompensation at first presentation were observed in 63% of the patients. Six-year survival was 54% in compensated and 21% in decompensated patients. No significant differences in survival were found between alcoholics and nonalcoholics. Leading causes of death were liver failure (49%), hepatocellular carcinoma (22%), and bleeding (13%). The prognostic role of 21 variables was evaluated separately in compensated and decompensated patients by the Cox's regression model. The following variables were found to be significant predictors of death risk in compensated patients: male sex, HBsAg positivity, age, prothrombin time prolongation, and esophageal varices. In decompensated disease the significant indicators of death risk were: hepatocellular carcinoma, encephalopathy, hemorrhage, SGOT, esophageal varices, gamma globulins, prothrombin time prolongation, continued abuse of alcohol, HBsAg positivity, gamma glutamyl transpeptidase, and cholinesterase. A simple prognostic index based upon the relative risk coefficient of the significant variables is suggested.Members of the Liver Study Group are: Maria Caltagirone, Gabriella Filippazzo, Giovanni Gatto, Gandolfo Giannuoli, Silvio Margin, Guiseppe Malizia, Lorenzo Maniaci, Maria Pia Marcenó, Alberto Maringhini, Rocco Micciolo, Salvatore Orsini, Fabio Pace, Ugo Palazzo, Linda Pasta, Giuseppina Russo, Rosa Giovanna Simonetti, Mario Spinello, Mario Traina, Mario Valenza, Maria Vinci, Giovanni Vizzini. 相似文献
996.
Prof. Dr. med. N. Dickgießer Dr. med. S. in der Stroth Prof. Dr. med. W. Wundt 《Infection》1986,14(2):82-85
Zusammenfassung In der Studie wurde untersucht, inwieweit durch Zugabe von Ciprofloxacin die antibakterielle Wirkung der Pipemidsäure sowie von Minozyklin, Gentamicin, Cefazolin, Mezlocillin oder Ampicillin gegenüber resistenten bzw. mäßig empfindlichen Testkeimen der SpeziesEscherichia coli, Klebsiella pneumoniae/Klebsiella oxytoca, Pseudomonas aeruginosa undStaphylococcus aureus beeinflußt wird. Die Untersuchungen ergaben eine synergistische Wirkung mit Pipemidsäure bei allen geprüften Spezies. Die Kombination mit Gentamicin ließ beiE. coli undK. pneumoniae/K. oxytoca Synergismus, beiP. aeruginosa undS. aureus additive Wirkung erkennen. Auch Minozyklin hatte mit Ciprofloxacin eine synergistische Wirkung, jedoch nur beiS. aureus. Bei den anderen Spezies und Antibiotikakombinationen war weder ein Synergismus noch ein Antagonismus festzustellen.
Studies on the synergism of ciprofloxacin with -lactam antibiotics, gentamicin, minocycline and pipemidic acid
Summary UsingEscherichia coli, Klebsiella pneumoniae/Klebsiella oxytoca, Pseudomonas aeruginosa andStaphylococcus aureus strains, we examined a possible influence of pipemidic acid, minocycline, gentamicin, cefazolin, mezlocillin and ampicillin on the antibiotic activity of ciprofloxacin. We found in all bacterial species synergistic influence by pipemidic acid. When ciprofloxacin was combined with gentamicin, synergism was observed inE. coli and inK. pneumoniae/oxytoca, additive effects inP. aeruginosa andS. aureus. In combination with minocycline we demonstrated synergism inS. aureus only. In all other bacterial species and antibiotic combinations we found neither synergism nor antagonism.相似文献
997.
The effect of 2,3-dimercaptopropane sodium sulfonate on mercury retention in rats in relation to age
The effectiveness of DMPS (sodium 2,3-dimercaptopropane-1-sulfonate) in reducing inorganic mercury retention was studied in 2-, 6-, and 28-week-old albino rats. 203Hg was administered IP. The chelating agent DMPS was administered by IP injection at a dose of 250 mol/kg body weight three times, 1 day after 203Hg administration and at 24 h intervals thereafter. The whole body retention determined 1, 2, 3, and 6 days after 203Hg administration showed that DMPS decreased the body retention of mercury in all age groups, being about twice as effective in adult compared to suckling rats. The reduced effectiveness was due to the reduced efficacy of DMPS in reducing kidney retention in young animals. In other organs the effectiveness of DMPS was not age dependent. These and previous results obtained with different chelating agents and other metals indicate that age might be an important factor in chelation therapy in general. 相似文献
998.
维生素A和维生素D是与儿童健康密切相关的两种脂溶性维生素,充足的维生素A、维生素D营养对儿童早期发展及疾病的防治具有积极的作用,缺乏和不足均会影响儿童健康。针对儿童保健医生和儿童家长对维生素A、维生素D的营养现状、缺乏原因及危害、防治措施、安全性等方面所存在的一些疑虑,中华预防医学会儿童保健分会组织国内相关专家,就上述问题结合国内外相关研究展开了充分讨论,基于现有研究成果,达成如下共识,希望对我国儿童维生素A、维生素D的临床应用提供参考. 相似文献
999.
1000.
目的 探讨在轻、中度脑梗塞急性期使用胞二磷胆碱的临床疗效。方法 本文选择轻度脑梗塞急性期5 2例 ,在使用抗凝、溶栓治疗的基础上加用胞二磷胆碱作治疗组 ,另选择 31例不加用胞二磷胆碱作对照组进行临床疗效观察。治疗组使用胞二磷胆碱 0 .5加入 10 %葡萄糖注射液 2 5 0ml,一日一次 ,静滴 ,十天为一疗程 ,连用 1-3个疗程。结果 治疗组有效率为 92 .31% ,其中显效率 36 .5 4% ;对照组 5 4.84% ,显效率 16 .13% ,显著低于治疗组 (P <0 .0 1)。疗程观察以第三个疗程为宜 ,其有效率占治疗组有效率的 5 8.33%。结论 胞二磷胆碱在脑梗塞急性期使用 ,主要是促进脑梗塞可逆性组织损伤的恢复 ,防止脑缺血后改变的加重 ,使脑细胞活化 ,促进脑细胞机能的修复 ,是一种既安全可靠 ,又经济实用的脑细胞活化剂。 相似文献